Your friend needs to consider local laws relating to the making
of such a document to get a specific answer. Generally, the law
provides safeguards making sure that the terms of the document are
followed. Also, at the request of an interested party, such as a
close relative, the law may allow for review of the conduct of the
agent.
Depending on the law, certain medical procedures, for example,
psychosurgery, may only be carried out if your friend (the maker
of the document) has specifically given her agent the power to make
that decision.
The law may allow for more than one agent to be appointed so that
accountability to each other is required. Some guidance about the
conduct of those who are providing a service covered by the terms
of the legal document may also be covered in the law. For example,
it may be stated that service providers must follow the instructions
of the document and/or the agent.